Runels : Thank you for having me. Just to echo what you just heard, sex is much more than about just having fun. My thinking that perhaps, as you guys do, some of the pathology that applies to the penis may apply to the clitoris, and maybe some of these women are suffering from actual genital histopathology, not just psychogenic problems. Obviously, this is not a new idea. This is from, this month, over 9, papers indexed in PubMed about platelet rich plasma. There are many more.
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Runels : Thank you for having me. Just to echo what you just heard, sex is much more than about just having fun. My thinking that perhaps, as you guys do, some of the pathology that applies to the penis may apply to the clitoris, and maybe some of these women are suffering from actual genital histopathology, not just psychogenic problems.
Obviously, this is not a new idea. This is from, this month, over 9, papers indexed in PubMed about platelet rich plasma. There are many more. They have these effects. These are good things for the genitalia. Down-regulating autoimmune response, proliferation of fibroblasts, new angiogenesis, the adipocytes enlarge and multiply — think labia majora, collagen production, neurogenesis and maybe some glandular function.
No granulomas, no serious infection. PRP is what your body makes to heal when you do your surgeries and help prevent infection. Obviously, there are always certain things that can happen, bruising and such, but if you have a serious life-threatening complication from PRP, you will have the first recorded in all of that 9, plus papers.
We have commercially available methods for preparing it, within 5 or 10 minutes of the bedside, and the devices are FDA approved. We have split-scalp studies showing that PRP helps alopecia areata better than triamcinolone. More hair growth that comes in thicker.
What do we have in the genital space? We have lichens sclerosus. We did some before and after pictures where you use stem cells mixed with PRP, and before and after pictures show improvement.
We took the same idea and just used PRP. Andrew Goldstein worked with me on this, and we had two blinded dermatopathologists. The protocol was biopsy, PRP, wait six weeks later, another PRP injection, and then six weeks after that, another biopsy.
Two blinded dermatopathologists out of George Washington University did not know the before or the after. We showed statistical improvement in both the histology and symptomatology. Of course if you look at the gross pictures, lady on the left as you guys know, she has pain wearing her blue jeans. The lady on the right is back to making love to her husband. We extended it because it worked. We published this past January in the journal of the American Academy of Dermatology.
You have some science to go do this now. It had been 12 years since she had had sexual intercourse, penis and vagina intercourse, with her loving husband … 12 years.
She was being followed by a dermatologist on high dose clobetasol. That same doctor, Casabona, repeated his study with lichen sclerosus in men [BXO], and showed with just PRP alone … This study of 45 men with repeat treatments … It is cumulative, 2 to 10 treatments, the same thing.
All of them stopped their steroids. None of them started back. Only one went on to have circumcision. For some reason, thankfully, they threw in one woman just for good measure, and showed that it helped her incontinence. They just tucked that in as an aftermath. Ronald Virag , as you guys know as the legendary vascular surgeon who was first to present the idea of intracavernosal injections for erectile dysfunction, out of Paris. He showed that PRP works better with few side effects.
You see the side effect is the erectile function improves. He showed the same thing, actually, in his studies that erectile dysfunction improves by an average of about 7 on that 5 to 25 point scale. This is looking at post-operative adhesions, lots of studies looking at scarring with microneedling and PRP. Sclafani did some studies in the cosmetic space looking at increased collagen production and fibroblast activity, and never a neoplasia documented. People worry about that.
This is not indiscriminate blindness blind growth. Physiatrist for the past ten years has been using PRP, your sports medicine doctors.
Now, when you palpate it, consider injecting with PRP instead. The science is there that it should help and it seems to be helping. Here is a look at a gentleman who did … He took the mesh out and then he patched the hole with a gel form of PRP and showed benefit. Just another place where we need some research done. Here, we have rat studies looking at inflammation. I was doing this and expecting not this to happen.
They showed new endothelial cell growth and increased nitric oxide activity in the dorsal nerve. Would that be helpful in the clitoris? Probably, but the interesting thing is the adipocyte-derived stem cells were attacked and they died. The postulate was the improvement was from the growth factors. I have seen what [inaudible ] have seen in that when you inject this in the penis, erectile function goes up on the average of about 5 to 7 per injection. Think about nerve repair.
We have rat studies modeling prostrate surgery, showing that the nerves improved with PRP and so we have, again, another clear place where we need studies if you add this now to the usual protocol for rehabilitating the penis post-prostate surgery … would you see benefit?
We have seen that in some of our patients who are a year or two out who failed the rehabilitation part of that. Would that help your patients who have, say, numbness and decreased function from riding their bikes too much, or trauma?
We found that it works better. Think infiltrating and getting ready to put in the mesh. Sometimes it lasts longer. The interesting idea is what might be happening with those [inaudible ]. They become more active, and does that help with sexual function? The other place we put it is in the actual corpus cavernosum of the clitoris. We use [inaudible ] ultrasound visualization and see it flow down into the body of the clitoris by the pubic ramus and the wave form goes to what you see in a flaccid penis to what you see in an erect penis.
Just 30 more seconds. The question here is how would you combine it with your energy source? It works great in the face if you do laser and follow it with PRP … better results, faster healing.
Is it going to … We need people to help us work out the algorithms. Not everybody has laxity, but when you have something, when do you use which treatment and when do you combine it with PRP? This is possible helps.
I am done. Thank you very much for having me. I put all these references at that website , if you want to go download them. Thank you. You guys have a wonderful conference. More about the Cellular Medicine Association. From an open-mike discussion sponsored by the Cellular Medicine Association for our members only. Charles Runels: So thank you guys for coming. We have quite a few questions. This came out today. So you can do the same thing. Now, if you go onto our … Well, let me give you specifics of what I would do right now.
Wait a second. Let me paste it. So wherever you can put that on a Facebook page, if you have it. Forget vampire facials! You can go into an email that can be simply three lines.
Now I put a whole video just about that. I want to show you. If you go to the Vampire Facelift page or the O-Shot page, and then you go to the marketing part. Let me log on. Let me go to the marketing so you can see. These are efficient,  ethical ways to help you heal more people who are suffering. So let me get to where you can see this. If you want to make a do list for this call, I would say one of the things would be go to this page, and go to  this one.
Leveraging the national press to bring patients to your office.
Tag: charles runels
Female genital rejuvenation is a hot topic, and the procedures are growing in popularity, thanks to more media awareness of this type of surgery. This comprehensive and highly visual text covers the important issues of patient selection and patient consultation as well as fully covering all the different operative techniques along with accompanying surgical video. There is a special focus on dealing with complications and how to deal with secondary cases. Sold by: Amazon. Skip to main content Charles Runels.
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